Endocrine Abstracts

Introduction: Insulin resistance is quite common among obese individuals. Lifestyle interventions like diet interventions and regular physical activity are still important and safe first-line therapy.The aim of this study was to assess the effects of diet and physical activity-induced weight loss on insulin resistance in extremely obese patients.Methods: Forty-four patients (mean age 41.05±10.23 years) were consecutively recru...

Background: It has been shown that hypothyroidism is associated with atherosclerosis. The presence of atherosclerosis process could be registered by use of some Doppler Ultrasound parameters (DUP) – intima-media complex thickness (IMCT) and systolic velocity (SV). In this study we present initial DUP on the lower limb artery in treatment-naïve hypothyroid females and the influence of thyroid hormone levels and some metabolic components.Methods ...

Background: Serum paraoxonase-1 (PON-1) activity is decreased in clinical conditions associated with low high density-cholesterol (HDL-C), increased lipid peroxidation and low-grade chronic inflammation such as in type 2 diabetes mellitus (T2DM). Although many studies have shown that some poly unsaturated fatty acids (PUFA) modulate cardiovascular risk in T2DM, until now there is no data about the association of any fatty acid (FA) with PON-1 activity. This study aims to inves...

Bacground: In type 2 diabetes mellitus (T2DM), the level of polyunsaturated fatty acids (PUFA), is usually decreased, and could be accused for metabolic disturbance, chronic inflammation, and accelerated atherosclerosis. The aim of this study was to determine if there is any relationship between composition of plasma phospholipids PUFAs and parameters of metabolic syndrome.Methods: The study was cross-sectional. Fifteen T2DM patients 63.22±7.20, BMI...

Adrenal incidentalomas are referred as clinically silent adrenal masses discovered incidentally during diagnostic testing or treatment for conditions not related to suspicion of adrenal disease. Certain percent of them are hormonally active and autonomous cortisol secretion is reported with increasing frequency. The aim of the study was to assess value of 1mg-DST in subclinical Cushing’s syndrome (CS) compared to the other forms of adrenal incidentalomas. We have evaluate...